You are here:   Academia > The Stem Cell Wars are Over
 

Recognising if not the sanctity of the human embryo, then at least some form of moral status, the Lancet in 2001 declared that "...creating embryos with no purpose other than to use them as a source of stem cells is ethically unacceptable."

But the scientific excitement and alleged medical potential of embryonic stem cells (arguably amplified by the politics of abortion, which also implicitly devalues the human embryo), resulted in the widespread abandonment of such principles, with a huge expansion of human embryo research, new and ever more liberating legislation in the UK, including last year's law allowing the cloning of human-animal hybrids, and outcry in the US at the "Bush ban" on federal funding for many forms of embryonic stem cell research.

The paradox is that while 2009 might have seen new UK legislation combining with a new US president to open the floodgates for human embryo research, the likelihood is that such research may instead slow to a trickle.

While still carrying the therapeutic hazards of embryonic stem cells, including tumour formation, iPSCs offer a far easier and cheaper methodology than either cloning human embryos or obtaining stem cells from more traditionally produced embryos (i.e. on a Petri dish in an IVF clinic). So even those still convinced that embryonic stem cells, rather than adult ones, hold the key to the future, are more likely to pursue their aims with human iPSCs, not embryo-derived cells. Equally importantly, adult stem cell advances, often dramatic, now appear almost weekly - from tracheal transplants to the generation of a prostate from a single adult stem cell. These cells are safe, relatively accessible and avoid immune rejection (being derived from the patient himself, not other individuals). Adult stem cells also start with a medical and biological advantage: tissue repair is their evolved purpose. Repairing diseased adult tissue is hardly the evolutionary function of the embryonic stem cell.

View Full Article
 
Share/Save
 
 
 
 
Alexander
February 9th, 2009
1:02 AM
Dear Mr Kaufman, would Stanford be reliable enough as a source for hESC? Or is Wikipedia the only scientific source you acknowledge? http://ora.stanford.edu/hesc/default.asp Will I have to assume that your name is made up?

Sir Desmond Kaufman
February 5th, 2009
11:02 PM
To infinity and beyond indeed. I don't know what hESC is and i got no hits on Wikipedia, so I'll have to assume that you're making it up. I'm guessing that ESC stands for embryonic stem cell, but what is the "h" for? No offence Thomas Friedl, but your name sounds made up.

Thomas Friedl
February 4th, 2009
11:02 PM
I am writing to you from Germany. What Neil Scolding is saying finds some affirmation in what recently happened over here. We just had a "stem cell war" which started in late 2006 when the German research foundation DFG published a paper calling for liberalisation of the Stem Cell Act. The Stem Cell Act stipulates that only embryonic stem cells (hESC) derived from human embryos before a certain cut-off date are eligible for importation for "high-ranking" research projects approved of by a special hESC ethics committee and in pursuance of a license issued by the Robert Koch Institute. The cut-off date used to be January 1, 2002. Derivation of hESC from human embryos is banned by our Embryo Protection Act, anyway. During the stem cell debate, more recently derived hESC have been depicted as absolutely indispensable by the German hESC research community. Finally, after much debate, in April 2008, the law was changed and the cut-off date was shifted to May 1, 2007, now allowing importation of many, many more recently established hESC. The new law took effect on August 21, 2008. But what happened? Quite contrary to what you might expect, there was no rush. Only four importation licenses have been granted since then. Most astonishingly, all of them relate to "old" NIH-registered hESC lines (established well before January 1, 2002) which had been readily eligible before as well. What can we conclude from this? Why are German hESC researchers not taking advantage of the liberalised law? Neil Scolding may be quite right: the embryonic stem cell wars appear to be over. This seems to be true for Germany, and probably beyond.

Prof David Alber Jones
February 4th, 2009
10:02 AM
Thank you for this helpful presentation of where we are with stem cell research. The public has been persuded to back embryonic stem cell research just as scientists are moving on to adult stem cells and iPS cells. How wonderfully ironic. Hopefully we now move beyond the culture wars and get on with science that is both ethical and effective.

Sir Desmond Kaufman
February 3rd, 2009
3:02 AM
I am the representative from the Stem Cell Awesomeness Group in Brunswick, Maine. It is a very official group that I set up on facebook. I think that this article is very good for those people who do not have to write a 5+ page paper and prepare a debate, which will be moderated by a waxy-haired, tie wearing, animal loving, pen twirling supreme member of the teacher's guild. A person who did have to write a 5+ page paper and prepare a debate on stem-cell research, then this article would prove completely useless. Also, the author, Neil Scolding, should change his last name to something like "Down".

Post your comment

CAPTCHA
This question is for testing whether you are a human visitor and to prevent automated spam submissions.